EXPERIMENTAL »RUNDE« VIRUS INFECTIONS IN EMBRYONATED EGGS AND CHICKENS
Identifieur interne : 001751 ( Main/Exploration ); précédent : 001750; suivant : 001752EXPERIMENTAL »RUNDE« VIRUS INFECTIONS IN EMBRYONATED EGGS AND CHICKENS
Auteurs : T. Traavik [Norvège]Source :
- Acta Pathologica Microbiologica Scandinavica Section B Microbiology [ 0304-131X ] ; 1978-09.
English descriptors
- Teeft :
- Acta, Acta path, Amniotic, Arbovirus, Baby mouse, Blood specimens, Bmldso, Cell cultures, Chick, Embryo, Embryonated, Embryonated eggs, High antibody titres, Inoculated, Microbiol, National institute, Nrundecc virus, Public health, Runde, Runde virus, Rundecc, Rundecc virus, Scand, Traavik, Viraemia, Virus, Virus strain.
Abstract
Three‐day‐old chicks and 11–12 day embryonated eggs were inoculated with 100 BMLD50 (baby mouse lethal doses) of Runde virus. Chicks were infected subcutaneously and eggs in the allantoic or amniotic cavities, in the yolk sac, or on the chorioallantoic membrane. »Runde« virus produced viraemia and antibody responses in 3‐day‐old chicks. The virus multiplied only in the amniotic cavity of the embryonated eggs and was detected in the brains of the embryos from day 5–9 p.i. Out of five eggs left to hatch, two hatched on time, while in three unhatched eggs the chicks were alive but extremely weak. Virus was detected in the brains of all five chicks, and high antibody titres were found in the two which hatched. These two chicks had »epilepsy‐like« attacks. The results suggested that one passage in chicks or eggs reduced the mouse pathogenicity of »Runde« virus. No antigenic difference between chick‐ and mouse‐passaged virus could be demonstrated by gel precipitation.
Url:
DOI: 10.1111/j.1699-0463.1978.tb00047.x
Affiliations:
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Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">EXPERIMENTAL »RUNDE« VIRUS INFECTIONS IN EMBRYONATED EGGS AND CHICKENS</title><author><name sortKey="Traavik, T" sort="Traavik, T" uniqKey="Traavik T" first="T." last="Traavik">T. Traavik</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:E993F2D4132439EB3FBE83CD228A8DB0F5CBBDFC</idno><date when="1978" year="1978">1978</date><idno type="doi">10.1111/j.1699-0463.1978.tb00047.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-Q6M8Z5L3-S/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000138</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000138</idno><idno type="wicri:Area/Istex/Curation">000118</idno><idno type="wicri:Area/Istex/Checkpoint">000855</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000855</idno><idno type="wicri:doubleKey">0304-131X:1978:Traavik T:experimental:runde:virus</idno><idno type="wicri:Area/Main/Merge">001783</idno><idno type="wicri:Area/Main/Curation">001751</idno><idno type="wicri:Area/Main/Exploration">001751</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">EXPERIMENTAL »RUNDE« VIRUS INFECTIONS IN EMBRYONATED EGGS AND CHICKENS</title><author><name sortKey="Traavik, T" sort="Traavik, T" uniqKey="Traavik T" first="T." last="Traavik">T. Traavik</name><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Virology, National Institute of Public Health, Oslo and Institute of Medical Virology, University of Tromsø, Tromsø</wicri:regionArea><wicri:noRegion>Tromsø</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Norvège</country><wicri:regionArea>Correspondence address: Institute of Medical Biology, University of Tromsø, N‐9001 Tromsø</wicri:regionArea><wicri:noRegion>N‐9001 Tromsø</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Acta Pathologica Microbiologica Scandinavica Section B Microbiology</title><title level="j" type="alt">ACTA PATHOLOGICA MICROBIOLOGICA SCANDINAVICA SECTION B MICROBIOLOGY</title><idno type="ISSN">0304-131X</idno><idno type="eISSN">1600-0463</idno><imprint><biblScope unit="vol">86B</biblScope><biblScope unit="issue">1‐6</biblScope><biblScope unit="page" from="299">299</biblScope><biblScope unit="page" to="302">302</biblScope><biblScope unit="page-count">4</biblScope><publisher>Blackwell Publishing Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="1978-09">1978-09</date></imprint><idno type="ISSN">0304-131X</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0304-131X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="Teeft" xml:lang="en"><term>Acta</term><term>Acta path</term><term>Amniotic</term><term>Arbovirus</term><term>Baby mouse</term><term>Blood specimens</term><term>Bmldso</term><term>Cell cultures</term><term>Chick</term><term>Embryo</term><term>Embryonated</term><term>Embryonated eggs</term><term>High antibody titres</term><term>Inoculated</term><term>Microbiol</term><term>National institute</term><term>Nrundecc virus</term><term>Public health</term><term>Runde</term><term>Runde virus</term><term>Rundecc</term><term>Rundecc virus</term><term>Scand</term><term>Traavik</term><term>Viraemia</term><term>Virus</term><term>Virus strain</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Three‐day‐old chicks and 11–12 day embryonated eggs were inoculated with 100 BMLD50 (baby mouse lethal doses) of Runde virus. Chicks were infected subcutaneously and eggs in the allantoic or amniotic cavities, in the yolk sac, or on the chorioallantoic membrane. »Runde« virus produced viraemia and antibody responses in 3‐day‐old chicks. The virus multiplied only in the amniotic cavity of the embryonated eggs and was detected in the brains of the embryos from day 5–9 p.i. Out of five eggs left to hatch, two hatched on time, while in three unhatched eggs the chicks were alive but extremely weak. Virus was detected in the brains of all five chicks, and high antibody titres were found in the two which hatched. These two chicks had »epilepsy‐like« attacks. The results suggested that one passage in chicks or eggs reduced the mouse pathogenicity of »Runde« virus. No antigenic difference between chick‐ and mouse‐passaged virus could be demonstrated by gel precipitation.</div></front></TEI><affiliations><list><country><li>Norvège</li></country></list><tree><country name="Norvège"><noRegion><name sortKey="Traavik, T" sort="Traavik, T" uniqKey="Traavik T" first="T." last="Traavik">T. Traavik</name></noRegion><name sortKey="Traavik, T" sort="Traavik, T" uniqKey="Traavik T" first="T." last="Traavik">T. Traavik</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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